2. Signaling Pathways
  3. PROTAC
  4. Ligands for E3 Ligase
  5. MDM2 Isoform
  6. MDM2 Inhibitor

MDM2 Inhibitor

MDM2 Inhibitor (1):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-148106
    MEL23 642072-49-9
    MEL23 is a MDM2 E3 ligase inhibitor that blocks the E3 ligase activity of the MDM2-MDMX complex. MEL23 inhibits Mdm2 and p53 ubiquitination in cells, reduce viability of cells with wild-type p53. MEL23 stabilizes MDM2 via a mechanism independent of p53 transcription.
    MEL23